- Release date: September 7, 2018
- Cover athletes: Joel Embiid C Philadelphia 76ers (PS4, Xbox One)
- In the WNBA, the San Antonio Stars relocated and became the Las Vegas Aces.
- San Antonio Spurs SG Manu Ginóbili was left on the Spurs roster when the game released, however he announced his retirement a week before the release date.
- During the middle of the season the Minnesota Timberwolves traded SG Jimmy Butler to the Philadelphia 76ers.